I problem with Imatrex is the constant warnings of people with a family history of heart problems and stuff... My family history is loaded with it. Pretty much everyone in my family actually. I do all I can to avoid anything that could negatively affect my heart. I am going to talk to my Dr about it more on Tues and see what she thinks. She didn't really talk to me that much about the drug before she prescribed it to me, thats my main concern... What if I shouldn't be taking it, ya know?